Journal: Revista da Associação Médica Brasileira

Article Title: Could signal peptide complement C1r/C1s, Uegf, and Bmp1, and epidermal growth factor-containing protein 1 be a therapeutic target in the pathogenesis of preeclampsia?

doi: 10.1590/1806-9282.20231027

Figure Lengend Snippet: Comparison of demographic characteristics and hematological and biochemical parameters of the study groups

Article Snippet: SCUBE1 levels were measured using the commercial enzyme-linked immunosorbent assay (ELISA) kits (Human SCUBE1 ELISA kit: Aviva Systems Biology, San Diego, USA).

Techniques: Comparison, Control, Sampling

Journal: Revista da Associação Médica Brasileira

Article Title: Could signal peptide complement C1r/C1s, Uegf, and Bmp1, and epidermal growth factor-containing protein 1 be a therapeutic target in the pathogenesis of preeclampsia?

doi: 10.1590/1806-9282.20231027

Figure Lengend Snippet: Univariate and multivariate regression analysis to identify independent predictors of preeclampsia

Article Snippet: SCUBE1 levels were measured using the commercial enzyme-linked immunosorbent assay (ELISA) kits (Human SCUBE1 ELISA kit: Aviva Systems Biology, San Diego, USA).

Techniques:

Journal: International Journal of General Medicine

Article Title: The Effects of Budesonide Inhalation Treatment on the Expression Levels of Serum IL-6, TGF-β1, and IgE and Pulmonary Function in Patients with Cough Variant Asthma and an Evaluation of Treatment Efficacy

doi: 10.2147/IJGM.S455872

Figure Lengend Snippet: Serum Cytokine Indicators with Three CVA Groups

Article Snippet: IL-5, IL-6, IL-8, TNF-α, and TGF-β1 levels were measured using ELISA kits (Proteintech, China).

Techniques:

Journal: International Journal of General Medicine

Article Title: The Effects of Budesonide Inhalation Treatment on the Expression Levels of Serum IL-6, TGF-β1, and IgE and Pulmonary Function in Patients with Cough Variant Asthma and an Evaluation of Treatment Efficacy

doi: 10.2147/IJGM.S455872

Figure Lengend Snippet: The ROC Curve Analysis of Complete Relief Group

Article Snippet: IL-5, IL-6, IL-8, TNF-α, and TGF-β1 levels were measured using ELISA kits (Proteintech, China).

Techniques:

Journal: Journal of Neurotrauma

Article Title: Relative Deficiency of Plasma A Disintegrin and Metalloprotease with Thrombospondin Type 1 Repeats 13 Activity and Elevation of Human Neutrophil Peptides in Patients with Traumatic Brain Injury

doi: 10.1089/neu.2018.5696

Figure Lengend Snippet: Plasma levels of HNP1-3 in healthy controls and TBI patients. Plasma concentrations of HNP1-3 in healthy controls and patients on admission (D0), day 1 (D1), 2 (D2), 3 (D3), and 5 (D5) post-TBI are shown as the medians ±95% confidential intervals. Symbols (*, **, ***, and ****) indicate the p values <0.05, <0.01, <0.005, and <0.0001, respectively. HNP1-3, human neutrophil peptides 1–3; n.s., not significant; TBI, traumatic brain injury; VWF, von Willebrand factor.

Article Snippet: Plasma levels of human neutrophil peptides 1–3 Plasma concentrations of HNP1-3 were determined by a commercially available ELISA method (Hycult Biothech, Plymouth, PA), following the manufacturer's recommendation.

Techniques:

Journal: Journal of Neurotrauma

Article Title: Relative Deficiency of Plasma A Disintegrin and Metalloprotease with Thrombospondin Type 1 Repeats 13 Activity and Elevation of Human Neutrophil Peptides in Patients with Traumatic Brain Injury

doi: 10.1089/neu.2018.5696

Figure Lengend Snippet: The diagram depicts how TBI may perturb the ADAMTS13/VWF function, resulting in thrombus formation. When a patient suffers from TBI, acute inflammation results in activation of neutrophils and vascular endothelial cells and release of HNP1-3 and VWF, respectively. Locally released HNP1-3 may bind to VWF, which blocks its proteolysis by ADAMTS13; additionally, increased VWF results in consumption of VWF. Inflammatory cytokines released during the acute inflammation may suppress the synthesis of ADAMTS13 from hepatic stellate cells and endothelial cells while triggering the release of VWF from endothelial cells. The net results are the reduction of ADAMTS13 or decrease in the ratio of ADAMTS13 to VWF. The relative deficiency may cause platelet adhesion and aggregation, and thrombus formation in the brain or elsewhere. ADAMTS13 (or A13), a disintegrin and metalloprotease with thrombospondin type 1 repeats 13; HNP1-3, human neutrophil peptides 1–3; TBI, traumatic brain injury; VWF, von Willebrand factor.

Article Snippet: Plasma levels of human neutrophil peptides 1–3 Plasma concentrations of HNP1-3 were determined by a commercially available ELISA method (Hycult Biothech, Plymouth, PA), following the manufacturer's recommendation.

Techniques: Activation Assay

Journal: Journal of Clinical Medicine

Article Title: The Diagnostic Value of Human Neutrophilic Peptides 1-3 in Acute Pediatric Febrile Illness

doi: 10.3390/jcm12206514

Figure Lengend Snippet: Different biochemical and hematological determinants in both groups. CRP—c-reactive protein, WBC—white blood cells.

Article Snippet: Plasma HNP1-3 levels were quantified by ELISA using a commercial human HNP1-3 ELISA Kit (HNP1-3; HyCult Biotechnology, Uden, The Netherlands, Kit#-HK317), with the measurable concentration ranging from 156 to 10,000 pg/mL.

Techniques:

Journal: Journal of Clinical Medicine

Article Title: The Diagnostic Value of Human Neutrophilic Peptides 1-3 in Acute Pediatric Febrile Illness

doi: 10.3390/jcm12206514

Figure Lengend Snippet: HNP1-3 levels in the different subgroups.

Article Snippet: Plasma HNP1-3 levels were quantified by ELISA using a commercial human HNP1-3 ELISA Kit (HNP1-3; HyCult Biotechnology, Uden, The Netherlands, Kit#-HK317), with the measurable concentration ranging from 156 to 10,000 pg/mL.

Techniques: Infection

Journal: Journal of Clinical Medicine

Article Title: The Diagnostic Value of Human Neutrophilic Peptides 1-3 in Acute Pediatric Febrile Illness

doi: 10.3390/jcm12206514

Figure Lengend Snippet: HNP1-3 levels according to the time elapsed from the first symptoms to HNP1-3 blood sampling. B = bacteria; V = viral.

Article Snippet: Plasma HNP1-3 levels were quantified by ELISA using a commercial human HNP1-3 ELISA Kit (HNP1-3; HyCult Biotechnology, Uden, The Netherlands, Kit#-HK317), with the measurable concentration ranging from 156 to 10,000 pg/mL.

Techniques: Sampling, Bacteria

Journal: Journal of Clinical Medicine

Article Title: The Diagnostic Value of Human Neutrophilic Peptides 1-3 in Acute Pediatric Febrile Illness

doi: 10.3390/jcm12206514

Figure Lengend Snippet: Correlations between HNP1-3 levels and different demographic parameters. BMI—body mass index.

Article Snippet: Plasma HNP1-3 levels were quantified by ELISA using a commercial human HNP1-3 ELISA Kit (HNP1-3; HyCult Biotechnology, Uden, The Netherlands, Kit#-HK317), with the measurable concentration ranging from 156 to 10,000 pg/mL.

Techniques:

Journal: Journal of Clinical Medicine

Article Title: The Diagnostic Value of Human Neutrophilic Peptides 1-3 in Acute Pediatric Febrile Illness

doi: 10.3390/jcm12206514

Figure Lengend Snippet: Age and different blood tests according to HNP1-3 tertiles. p 1 = 1 vs. 2, p 2 = 1 vs. 3, p 3 = 1 vs. 4, p 4 = 2 vs. 3, p 5 = 2 vs. 4.

Article Snippet: Plasma HNP1-3 levels were quantified by ELISA using a commercial human HNP1-3 ELISA Kit (HNP1-3; HyCult Biotechnology, Uden, The Netherlands, Kit#-HK317), with the measurable concentration ranging from 156 to 10,000 pg/mL.

Techniques:

Journal: Journal of Clinical Medicine

Article Title: The Diagnostic Value of Human Neutrophilic Peptides 1-3 in Acute Pediatric Febrile Illness

doi: 10.3390/jcm12206514

Figure Lengend Snippet: Logistic regression analysis of continuous parameters to predict the diagnosis of bacterial infection. CRP—c-reactive protein, WBC—white blood cells.

Article Snippet: Plasma HNP1-3 levels were quantified by ELISA using a commercial human HNP1-3 ELISA Kit (HNP1-3; HyCult Biotechnology, Uden, The Netherlands, Kit#-HK317), with the measurable concentration ranging from 156 to 10,000 pg/mL.

Techniques: Infection